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How do lungs grow?

Published in Lung Development 2 mins read

Lungs grow like a branching tree, starting in the womb with the formation of "branches" that become increasingly complex throughout pregnancy.

Here's a more detailed explanation:

  • Early Development (Pseudoglandular Stage): The lungs begin their development in the womb during the pseudoglandular stage. This stage is characterized by the formation of a tree-like structure. The main trunks of the developing lungs branch out, creating smaller and smaller airways.

  • Branching Morphogenesis: This is the key process driving lung growth. It involves the repeated division and differentiation of cells at the tips of the developing airways. These cells form buds that elongate and branch, creating the complex network of airways that will eventually allow for gas exchange.

  • Increasing Complexity: Throughout pregnancy, these "branches" continue to grow and become more complex. The airways divide and subdivide, forming the intricate network of bronchioles and alveoli that characterize the mature lung.

  • Alveolar Development: Alveoli are the tiny air sacs in the lungs where gas exchange takes place. The formation of alveoli is crucial for efficient respiration after birth. This process continues after birth, contributing to lung growth throughout childhood.

In summary, lung growth is a complex process involving branching morphogenesis and cellular differentiation that begins in the womb and continues after birth, ultimately forming the intricate structure necessary for breathing.

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