BOS rejection, or Bronchiolitis Obliterans Syndrome, is a significant complication following lung transplantation. It represents a chronic rejection process that impacts the transplanted lung(s).
Understanding Bronchiolitis Obliterans Syndrome (BOS)
BOS is characterized by the progressive obstruction of small airways in the transplanted lung(s), ultimately leading to a decline in lung function. It's a long-term problem that can significantly affect a patient's quality of life.
Symptoms of BOS
Individuals experiencing BOS often present with a range of symptoms that reflect their declining lung function. Common indicators include:
- Shortness of breath: A noticeable increase in difficulty breathing, especially with exertion.
- Decreased exercise or activity tolerance and endurance: Feeling more tired and less able to perform physical activities.
- Fatigue: Persistent tiredness and lack of energy.
Key Features of BOS
The following table summarizes key aspects of BOS:
| Feature | Description |
|---|---|
| Type of Rejection | Chronic (long-term) |
| Affected Organ | Transplanted lung(s) |
| Primary Mechanism | Obstruction of small airways |
| Consequence | Decreased lung function |
| Common Symptoms | Shortness of breath, decreased exercise tolerance/endurance, fatigue |
Impact on Lung Transplant Recipients
BOS is a serious complication for lung transplant recipients because it directly affects their ability to breathe and maintain an active lifestyle. The progressive nature of the disease requires careful monitoring and management to slow its progression and alleviate symptoms.
