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What is the pH of Lymph?

Published in Lymph pH 2 mins read

The pH of lymph is not a single fixed value, but rather it varies depending on the health status of the lymphatic tissue.

pH Variability in Lymph

Lymphatic fluid, which is crucial for immune function and waste removal, shows different pH levels based on whether the lymph nodes (LNs) are healthy or affected by disease. Our reference study provides key insights into this variation:


Lymph Node Condition pH Level Description
Normal LNs Approximately 8 Normal LNs exhibit a buffered, non-acidic environment.
Cancer-Involved LNs ≤ 7 Cancerous LNs have a more acidic pH.


Normal Lymph pH

  • Normal, healthy lymph nodes typically maintain a pH of approximately 8.
  • This alkaline (non-acidic) environment is supported by the buffering capacity of the lymph.


Lymph pH in Cancerous Conditions

  • When cancer is present in the lymph nodes, the pH tends to become more acidic, dropping to ≤ 7.
  • The increased acidity is often associated with the metabolic activities of cancer cells.


Importance of pH in Lymph

The pH of lymph can indicate different physiological states:

  • Alkaline pH in normal lymph suggests a healthy, balanced condition.
  • Acidic pH in cancer-involved lymph nodes may point to the presence of cancerous cells and their altered metabolism.
  • Monitoring pH levels could potentially be used as an indicator of lymphatic health.


By considering the condition of the lymph nodes, we can appreciate how much the pH of lymph may vary. The reference study clarifies that normal lymph is slightly alkaline, whereas cancer-affected lymph is more acidic.

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