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What are 10 Common Diseases of the Lymphatic System?

Published in Lymphatic Diseases 3 mins read

Here are 10 common diseases affecting the lymphatic system, based on available references and general medical knowledge:

The lymphatic system is a critical network of vessels, tissues, and organs that help to maintain fluid balance, fight infection, and remove waste from the body. Problems with this system can lead to various conditions.


Common Lymphatic System Diseases:

Disease Description Key Features
Hodgkin's Lymphoma A rare type of cancer that originates in the lymphatic system.

Characterized by the presence of Reed-Sternberg cells. Symptoms include swollen lymph nodes, fever, and night sweats.

Non-Hodgkin's Lymphoma A more common form of cancer arising from lymphocytes in the lymphatic system.

It is a diverse group of lymphomas with varying characteristics and progression rates. Symptoms often include swollen lymph nodes, fatigue, and weight loss.

Lymphedema Swelling that occurs due to a blockage or damage in the lymphatic system.

Often causes swelling in the arms or legs due to the accumulation of lymph fluid.

Lymphangitis Inflammation of the lymphatic vessels, usually due to infection.

Often appears as red streaks on the skin, accompanied by pain, fever, and swelling.

Lymphadenitis Inflammation of the lymph nodes, often caused by infection.

Characterized by swollen and tender lymph nodes.

Tonsillitis Inflammation of the tonsils, which are part of the lymphatic system.

Symptoms include sore throat, difficulty swallowing, and fever.

Splenomegaly Enlargement of the spleen.

Often results from various infections or blood disorders. Can cause abdominal pain and fullness.

Filariasis Parasitic infection of the lymphatic system caused by filarial worms.

Can cause severe lymphedema, particularly in the lower limbs.

Castleman disease A rare condition that involves overgrowth of lymphoid tissue.

May be localized or widespread, with varying symptoms including swollen lymph nodes.

Autoimmune Lymphoproliferative Syndrome (ALPS) A genetic disorder causing problems with lymphocyte function.

Characterized by chronic enlargement of the lymph nodes, spleen, and liver, and autoimmune issues.


In Detail:

Hodgkin's Lymphoma

As mentioned in the references, Hodgkin's lymphoma is a relatively rare cancer of the lymphatic system. It is distinguished from other lymphomas by the presence of specific cancer cells called Reed-Sternberg cells. This cancer usually starts in lymph nodes and can spread to other parts of the body.

Non-Hodgkin's Lymphoma

Also from the references, non-Hodgkin's lymphoma represents a more common and diverse group of cancers affecting the lymphatic system. It can involve various types of lymphocytes and is classified into many subtypes.

Lymphedema

Lymphedema, as indicated in the reference, is a condition involving tissue swelling. This occurs when the lymphatic system is unable to effectively drain lymph fluid. It can result from congenital issues, surgery, radiation, or infections.

Lymphangitis

The inflammation of lymphatic vessels, called lymphangitis, is often due to a bacterial infection. It presents with red streaks on the skin, which follow the path of the infected vessels.


It's important to consult a healthcare professional if you experience any symptoms related to the lymphatic system to receive a proper diagnosis and treatment plan.

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