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What does it mean when your lymphocytes are low?

Published in Lymphocyte Deficiency 2 mins read

Having low lymphocytes, a condition called lymphopenia, means you are at a higher risk of infection because lymphocytes help protect your body from infections.

Understanding Lymphocytes and Lymphopenia

Lymphocytes are a type of white blood cell that plays a crucial role in your immune system. They help fight off infections and diseases. When your lymphocyte count is lower than normal, it indicates that your body may have difficulty defending itself against pathogens.

Causes of Low Lymphocytes

According to the reference, the main risk factor for lymphopenia worldwide is poor nutrition. However, other factors can also contribute:

  • Infections: Certain viral, bacterial, and fungal infections can lower lymphocyte counts.
  • Diseases: Autoimmune disorders, such as lupus and rheumatoid arthritis, and certain cancers, like leukemia and lymphoma, can affect lymphocyte production or survival.
  • Medicines: Some medications, including corticosteroids and chemotherapy drugs, can suppress lymphocyte production.
  • Other Factors: Conditions like HIV/AIDS, inherited immune deficiencies, and radiation exposure can also lead to lymphopenia.

Risks Associated with Low Lymphocytes

The primary risk associated with low lymphocytes is an increased susceptibility to infections. This can include:

  • Common infections like colds and flu.
  • More serious infections like pneumonia and sepsis.
  • Opportunistic infections, which are infections that rarely affect people with healthy immune systems.

Diagnosis and Treatment

If you suspect you have low lymphocytes, it's important to see a healthcare provider. They can perform a blood test to determine your lymphocyte count and identify any underlying causes. Treatment for lymphopenia depends on the underlying cause and may include:

  • Addressing nutritional deficiencies with dietary changes or supplements.
  • Treating infections with antibiotics, antivirals, or antifungals.
  • Managing autoimmune disorders with immunosuppressants.
  • Adjusting or discontinuing medications that are suppressing lymphocyte production.

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