The full form of MCL is Mantle Cell Lymphoma. When the term "MCL cells" is used, it refers to the specific malignant B-cells that are characteristic of this type of lymphoma.
What is Mantle Cell Lymphoma (MCL)?
Mantle Cell Lymphoma (MCL) is a subtype of B-cell non-Hodgkin lymphoma (NHL). It is considered a distinct entity due to its unique clinical, biological, and genetic features. It arises from B-lymphocytes located in the mantle zone of lymphoid follicles.
Key Characteristics of MCL
Based on the information provided, here are some key facts about Mantle Cell Lymphoma:
- Rarity: It is a relatively rare form of lymphoma.
- Incidence: The annual incidence is approximately one case per 200,000 people.
- Prevalence among NHLs: MCL constitutes around 5% of all non-Hodgkin lymphomas.
- Gender Predominance: It is more common in men, with a male-to-female ratio of roughly 3 to 1.
- Age of Diagnosis: The median age at diagnosis is typically between 60 and 70 years old.
Understanding that MCL is a specific type of B-cell lymphoma helps explain why the term "MCL cells" is used to denote the particular cancerous cells associated with this disease.
