The primary difference between Hodgkin's lymphoma and non-Hodgkin's lymphoma lies in the specific type of cell present: the Reed-Sternberg cell.
Here's a breakdown:
- Hodgkin's Lymphoma: Characterized by the presence of Reed-Sternberg cells.
- Non-Hodgkin's Lymphoma: Lacks Reed-Sternberg cells. This category includes many different subtypes of lymphoma.
To further clarify the distinctions, consider the following table:
| Feature | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma |
|---|---|---|
| Reed-Sternberg Cells | Present | Absent |
| Subtypes | Fewer subtypes | Many subtypes |
| Origin | Often starts in upper body lymph nodes | Can start in lymph nodes throughout the body |
The presence or absence of Reed-Sternberg cells is crucial for diagnosis and classification, ultimately influencing treatment strategies.
