Malaria is transmitted to humans through the bite of infected female Anopheles mosquitoes.
Here's a more detailed breakdown:
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The Vector: Only female Anopheles mosquitoes are capable of transmitting malaria. Male mosquitoes feed on nectar and do not bite humans.
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The Parasite: Malaria is caused by parasitic protozoans belonging to the genus Plasmodium. Several species of Plasmodium can infect humans, including P. falciparum, P. vivax, P. ovale, P. malariae, and P. knowlesi.
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The Transmission Cycle:
- Infection of the Mosquito: A female Anopheles mosquito becomes infected when she takes a blood meal from a person already infected with malaria parasites.
- Parasite Development: Inside the mosquito, the Plasmodium parasites undergo a complex developmental cycle. This process takes several days.
- Transmission to Human: Once the parasites have developed into their infective stage (sporozoites) within the mosquito's salivary glands, the mosquito can transmit malaria to another person when she takes another blood meal. The sporozoites are injected into the human bloodstream during the bite.
- Human Infection: Once in the human bloodstream, the sporozoites travel to the liver, where they multiply. After a period of incubation, the parasites are released from the liver and infect red blood cells. It's within the red blood cells that the parasites multiply further, causing the symptoms of malaria.
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Other Rare Transmission Methods: While mosquito bites are the primary mode of transmission, malaria can also be transmitted in rare cases through:
- Congenital Malaria: A pregnant woman with malaria can transmit the infection to her unborn child.
- Blood Transfusion: Malaria can be transmitted through contaminated blood transfusions.
- Organ Transplantation: Rarely, malaria can be transmitted through organ transplantation.
- Sharing of Needles: Sharing needles with an infected person can also transmit the disease, though this is uncommon.
In summary, malaria is primarily transmitted through the bite of infected female Anopheles mosquitoes, which inject Plasmodium parasites into the human bloodstream. Understanding this transmission cycle is crucial for implementing effective malaria prevention and control strategies.