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What does FOLFOX stand for?

Published in Medical Abbreviations 1 min read

FOLFOX is an acronym representing a combination chemotherapy regimen used to treat colorectal cancer. It stands for:

  • FOL - Folinic acid (Leucovorin)
  • FOX - Fluorouracil (5-FU)
  • OX - Oxaliplatin

This regimen involves administering these three drugs in a specific sequence and dosage to combat cancerous cells. Several variations of the FOLFOX regimen exist, such as FOLFOX-4, FOLFOX-6, modified FOLFOX-6 (mFOLFOX-6), and FOLFOX-7, each differing slightly in the dosages and schedules of drug administration.

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