PBC stands for Primary Biliary Cholangitis.
Primary Biliary Cholangitis (PBC) is a chronic liver disease that primarily affects the small bile ducts within the liver. These ducts become inflamed and damaged, eventually leading to scarring (cirrhosis) and impaired liver function. The condition is considered an autoimmune disease, where the body's immune system mistakenly attacks its own liver cells.
While the exact cause of PBC is unknown, genetic predisposition and environmental factors are believed to play a role. Symptoms can vary widely, ranging from fatigue and itching to more severe complications like liver failure. Treatment focuses on slowing the progression of the disease, managing symptoms, and preventing complications. Ursodeoxycholic acid (UDCA) is a commonly prescribed medication that helps improve bile flow and protect liver cells. In advanced cases, a liver transplant may be necessary.