In a medical context, DDC can stand for Duration of Disease Control.
Based on the provided reference, Duration of Disease Control (DDC) is defined as follows in a specific study context:
- It is the same as Progression-Free Survival (PFS).
- If FOLFOX (a chemotherapy regimen) was reintroduced, DDC is calculated by adding the initial PFS and the PFS of the reintroduction.
- An exception to the above rule is if progression occurred at the first evaluation after FOLFOX reintroduction.
In essence, DDC aims to measure how long a treatment effectively keeps a disease stable, without it progressing. If the treatment is re-administered after an initial period of control, the duration of control from both instances is combined to give a more comprehensive assessment.
