The full form of CRS in a hospital setting can refer to Cytokine Release Syndrome.
Cytokine Release Syndrome (CRS) Explained
Cytokine Release Syndrome (CRS) is a systemic inflammatory response that can occur in patients, often triggered by infection or immunotherapy treatments.
- Definition: Cytokine Release Syndrome (CRS), sometimes called cytokine storm or cytokine-associated toxicity, is a condition that develops when your immune system responds too aggressively to infection. It can also happen after certain types of immunotherapy, such as CAR T-Cell Therapy.
- Causes: It is caused by a large release of cytokines (small proteins important in cell signaling) into the bloodstream, leading to systemic inflammation.
- Triggers: Common triggers include:
- Infections
- Certain immunotherapies like CAR T-cell therapy
- Symptoms: Symptoms can vary widely in severity, ranging from mild flu-like symptoms to life-threatening organ dysfunction.
- Treatment: Treatment approaches depend on the severity of the syndrome and may include supportive care, anti-inflammatory medications, and specific therapies to target the underlying cause.
