Methotrexate, followed by misoprostol, can terminate a pregnancy up to 49 days gestation.
The combination of injections and oral medication used to terminate a pregnancy, specifically one less than 49 days' gestation, involves the following:
- Methotrexate: Administered via injection (intramuscularly) at a dose of 50 mg/m2, and orally at 50 mg.
- Misoprostol: Administered vaginally following the methotrexate.
This combination has a success rate of 90% in causing an abortion when the pregnancy is less than 49 days.