A Lupus Erythematosus (LE) cell, also known as Hargraves cell, is a specific type of cell found in certain autoimmune conditions.
Understanding the LE Cell
The LE cell is essentially a neutrophil or macrophage that has engulfed the altered nuclear material of another cell. This engulfed material is called a hematoxylin body, also referred to as an LE body.
- Neutrophil/Macrophage: A type of white blood cell responsible for engulfing foreign material and cellular debris.
- Phagocytosis: The process by which a cell engulfs another cell or particle.
- Hematoxylin Body (LE Body): Denatured nuclear material that has been absorbed by the neutrophil or macrophage.
In summary, the Hargraves cell, or LE cell, represents a phagocytic cell that has engulfed denatured nuclear material, a hallmark feature observed particularly in Lupus Erythematosus.
