A disease is simply an abnormal condition that negatively affects the structure or function of part or all of an organism, and it's usually not due to an immediate injury. These conditions are often recognized as medical problems associated with specific signs and symptoms.
In more detail:
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Abnormal Condition: Disease deviates from the normal healthy state. This can involve changes in the body's structure (anatomy) or how it functions (physiology).
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Adversely Affects: The condition has a negative impact on the organism, potentially causing discomfort, pain, impaired function, or even death.
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Structure or Function: Diseases can manifest through alterations in physical structures (e.g., tumors) or in the way the body works (e.g., diabetes affecting sugar metabolism).
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Not Immediately Due to External Injury: This differentiates disease from trauma or injury. While an injury can lead to a disease (e.g., infection after a wound), the disease itself is not the direct result of the external force.
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Signs and Symptoms: Diseases are often identified by observable signs (e.g., fever, rash) and felt symptoms (e.g., pain, fatigue).
Examples:
- Diabetes: A disease where the body doesn't properly regulate blood sugar levels, affecting various organ systems.
- Cancer: A disease characterized by uncontrolled cell growth that can invade and damage tissues.
- Infectious Diseases: Diseases caused by pathogens like bacteria, viruses, or fungi (e.g., the flu, COVID-19).
In essence, a disease disrupts the normal equilibrium of the body, leading to ill health.