Yes, DNS (Dextrose Normal Saline) infusion can cause fever as a potential side effect.
Explanation
DNS infusion, a common intravenous fluid used for hydration and electrolyte replenishment, can sometimes lead to adverse reactions in patients. While generally safe, potential side effects can occur. The reference material specifically lists fever as a possible side effect, along with others such as allergic reactions, shivering, and injection site complications.
Potential Mechanisms
While the exact mechanism isn't explicitly stated in the provided reference, a few possibilities exist:
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Pyrogenic Contamination: The infusion solution or the administration equipment could be contaminated with pyrogens (fever-inducing substances). Stringent manufacturing and handling protocols are in place to prevent this, but it remains a potential cause.
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Allergic Reaction: Although listed separately in the reference, an allergic reaction to a component of the solution or the IV administration set could manifest as a fever.
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Injection Site Infection: Infection at the injection site may cause a localized or systemic inflammatory response, which then causes a fever.
Summary
In conclusion, DNS infusion is associated with a risk of fever, even though such occurrences are ideally mitigated by stringent manufacturing and administration practices. It is important to monitor patients receiving DNS infusions for any signs of adverse reactions, including fever.