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Why is my saliva black?

Published in Medical Side Effects 2 mins read

Your saliva is likely black due to a reaction between bismuth (found in medications like Pepto-Bismol) and sulfur compounds naturally present in your saliva, forming bismuth sulfide.

Here's a more detailed explanation:

  • Bismuth's Role: Bismuth subsalicylate is the active ingredient in medications like Pepto-Bismol, commonly used to treat diarrhea and upset stomach.

  • The Chemical Reaction: When bismuth comes into contact with sulfur-containing compounds (proteins, amino acids, etc.) in your saliva, it creates bismuth sulfide (Bi2S3).

  • Bismuth Sulfide's Appearance: Bismuth sulfide is a blackish-brown, insoluble substance. This is what causes the darkening of your saliva.

  • Harmless Side Effect: According to Pepto-Bismol manufacturer information, this reaction is typically harmless and a normal side effect of taking bismuth-containing medications. It is temporary.

  • Other Possible Causes (Less Likely): While bismuth subsalicylate is the most probable cause given the context, less common reasons for dark saliva can include:

    • Certain medications other than bismuth containing drugs.
    • Fungal infections (rare).
    • Dietary factors (very dark foods in large quantities).
    • Exposure to heavy metals (extremely rare).

When to be Concerned:

While typically harmless, if you experience black saliva without taking bismuth-containing medications, or if it is accompanied by other symptoms like pain, bleeding, or a foul odor, consult a healthcare professional.

In summary, black saliva is most likely a harmless side effect of bismuth subsalicylate reacting with sulfur in your saliva. If you are concerned, check the ingredients of any medication you've taken, and consult your doctor if you have any other symptoms or are not taking bismuth containing drugs.

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