Currarino syndrome is a rare medical condition characterized by a specific triad of congenital anomalies. This condition was first described by Currarino et al. in 1981. [1]
Key Features of Currarino Syndrome
The syndrome is identified by the presence of three main features:
- Sacral Anomaly: This involves malformations of the sacrum, which is the bone at the base of the spine. These anomalies can include:
- Agenesis of the sacrum: Complete or partial absence of the sacrum.
- Agenesis of the coccyx: Absence of the tailbone.
- Hemisacrum: Only half of the sacrum is developed.
- Anorectal Malformation: This refers to birth defects affecting the anus and rectum. These can range in severity from mild to severe.
- Presacral Mass: This is a tumor-like growth located in front of the sacrum. These masses can vary in type, such as meningoceles, teratomas, or enteric cysts.
Characteristics and Details
Here's a table summarizing the features:
| Feature | Description |
|---|---|
| Sacral Anomaly | Malformations of the sacrum, coccyx, or hemisacrum. May include complete or partial absence. |
| Anorectal Malformation | Birth defects impacting the anus and rectum; varying levels of severity. |
| Presacral Mass | Tumor-like growth located anterior to the sacrum; includes meningoceles, teratomas, or enteric cysts. |
Clinical Presentation
The severity and presentation of Currarino Syndrome can be variable. Some individuals might have a complete triad of the three anomalies, while others might only have two. Clinical manifestations can range from mild and asymptomatic to more severe cases with complications.
Origin of the Name
Currarino Syndrome is named after the researchers, Currarino et al., who first described the syndrome in 1981. [1]
Conclusion
Currarino syndrome is a rare congenital disorder characterized by a combination of sacral anomalies, anorectal malformations, and a presacral mass. It is important to note the variable presentation of this syndrome.
