"G1 disease" is a term used in various medical contexts and can refer to several different conditions. It is not a specific disease itself but rather a descriptor used to categorize various disorders.
Here are some instances where "G1" is used in medical terminology:
- Chronic Kidney Disease (CKD) Stage G1: This stage is characterized by a normal estimated glomerular filtration rate (eGFR) above 90 ml/min/1.73m2, but with other tests revealing signs of kidney damage. Despite normal kidney function, individuals in stage G1 are considered to have early kidney disease.
- FOXG1 Syndrome: This genetic disorder is characterized by severe developmental delays, microcephaly, intellectual disability, movement disorders, and other complications. The name "FOXG1" comes from the specific gene responsible for the condition.
- APOL1 G1 variant: This is a genetic variant of the apolipoprotein L1 (APOL1) gene, associated with increased risk for proteinuric chronic kidney disease (CKD) in individuals with sickle cell disease.
- Myeloproliferative disorders (MPD): This is a broad category of blood disorders characterized by abnormal proliferation of blood cells in the bone marrow. While not directly referred to as "G1," these disorders can involve cell cycle control mechanisms relevant to the G1 phase of the cell cycle.
To understand which "G1 disease" you are referring to, more context is needed. Please clarify your question or provide additional information to obtain a specific answer.
