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Can a CBC test detect tuberculosis?

Published in Medical Testing 2 mins read

No, a complete blood count (CBC) test cannot directly detect tuberculosis (TB). While a CBC can reveal general information about your blood cells, it doesn't specifically look for the bacteria that causes TB.

Here's why:

  • CBC measures general blood cell counts: A CBC test measures the number of red blood cells, white blood cells, and platelets in your blood. These values can indicate various conditions, but not specifically TB.
  • TB tests focus on immune response or bacterial presence: Tests for TB infection or disease are designed to specifically detect the presence of TB bacteria or the immune response to the bacteria. Examples include:
    • Tuberculin skin test (TST): This test involves injecting a small amount of TB protein under the skin. A positive reaction indicates exposure to TB bacteria.
    • Interferon-gamma release assays (IGRAs): These blood tests detect the immune response to TB bacteria by measuring the amount of interferon-gamma released by your white blood cells.

In summary, a CBC test is a general blood test that doesn't have the ability to detect TB. Dedicated TB tests are necessary for diagnosing infection or disease.

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