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What is an IgM test?

Published in Medical Testing 2 mins read

An IgM test is a blood test that measures the level of IgM antibodies in your blood. IgM, or Immunoglobulin M, is a type of antibody produced by the body's immune system to fight off infections, particularly during the early stages of an infection.

Understanding IgM Antibodies

  • First Responder: IgM is typically the first antibody the body produces when it encounters a new antigen, such as a bacteria or virus.
  • Indicates Recent Infection: Elevated levels of IgM often indicate a recent or current infection.
  • Short-Lived: Unlike other antibodies like IgG, IgM levels tend to decrease relatively quickly after the infection has resolved.

Why is an IgM Test Performed?

An IgM test is performed to:

  • Detect recent infections: Help diagnose acute infections, as elevated IgM levels suggest a recent exposure to a pathogen.
  • Diagnose certain autoimmune diseases: Some autoimmune diseases can cause elevated IgM levels.
  • Evaluate immune system function: Assess the body's ability to produce antibodies in response to an infection.
  • Diagnose congenital infections in newborns: Detect infections acquired during pregnancy.

What Do the Results Mean?

  • High IgM Levels: May indicate a recent or current infection, such as:
    • Viral infections (e.g., mononucleosis, cytomegalovirus (CMV))
    • Bacterial infections (e.g., pneumonia)
    • Parasitic infections
    • Autoimmune disorders (e.g., rheumatoid arthritis, Waldenstrom macroglobulinemia)
  • Low IgM Levels: May indicate:
    • Immunodeficiency disorders
    • Certain medications that suppress the immune system

Important Considerations

It's important to remember that IgM test results should always be interpreted by a healthcare professional in conjunction with other clinical findings, medical history, and other laboratory tests. A single IgM test result is rarely diagnostic on its own.

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