The Erythrocyte Sedimentation Rate (ESR) and C-reactive protein (CRP) are both blood tests used to detect inflammation in the body. These tests are among the oldest laboratory tests still in use, according to the provided reference.¹⁻³
Understanding ESR and CRP
Here's a breakdown of what these tests are and how they are used:
Erythrocyte Sedimentation Rate (ESR or Sed Rate)
- The ESR test measures how quickly red blood cells settle at the bottom of a test tube.
- Increased inflammation causes red blood cells to clump together, making them fall faster, resulting in a higher ESR.
C-Reactive Protein (CRP)
- The CRP test measures the levels of a protein called C-reactive protein in the blood.
- CRP levels rise in response to inflammation.
Why are ESR and CRP Tests Used?
Both ESR and CRP are used as indicators of inflammation, which can be caused by:
- Acute conditions: such as injuries or infections.
- Chronic conditions: such as autoimmune disorders.
Key Differences Between ESR and CRP
While both tests detect inflammation, they differ in how they do it:
| Feature | ESR | CRP |
|---|---|---|
| Measures | Rate at which red blood cells settle | Level of C-reactive protein |
| Response Time | Slower response to inflammation | Faster response to inflammation |
In Summary
ESR and CRP are crucial laboratory tests for detecting inflammation. They serve as valuable tools for clinicians to identify and monitor inflammatory processes in the body, whether acute or chronic. These tests are an important part of diagnostic evaluation as stated in the provided reference.⁴⁻⁶
