There isn't one single "3 cream" universally recognized for melasma treatment. Melasma treatment often involves combinations of ingredients, and the specific combination depends on the severity and type of melasma. However, several triple-combination creams are used, and one FDA-approved option stands out.
FDA-Approved Triple Combination Cream: Tri-Luma®
Tri-Luma® (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) Cream is the only FDA-approved topical treatment for moderate-to-severe facial melasma. It's a triple combination cream indicated for short-term (up to 8 weeks) treatment and requires sun avoidance measures, including sunscreen use. https://www.triluma.com/
Other Triple Combination Creams Studied for Melasma
Research has explored other triple combinations, although they may not have the same level of FDA approval as Tri-Luma. For example:
- A study investigated a combination of 4% hydroquinone, 0.05% tretinoin, and 0.1% mometasone furoate cream with glycolic acid peels. https://pmc.ncbi.nlm.nih.gov/articles/PMC2800888/
- Another study showcased a new triple combination cream with isobutylamido-thiazolyl-resorcinol, retinoic acid, and dexamethasone, demonstrating effectiveness in melasma treatment. https://www.dermatologytimes.com/view/new-trio-combination-cream-efficacious-in-melasma-treatment
Important Note: The effectiveness of any melasma treatment varies among individuals. Consulting a dermatologist is crucial for proper diagnosis and personalized treatment plan. They can determine the best approach based on your skin type, melasma severity, and other factors.
