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What Hormones Cause Periods to Start?

Published in Menstrual Hormones 2 mins read

The decrease of estrogen and progesterone, coupled with a rise in prostaglandin, are the key hormones that trigger the start of a period.

How Hormones Influence Menstruation

The menstrual cycle is a complex process regulated by several hormones. Here’s a breakdown of the hormonal interplay that leads to menstruation:

  • Estrogen and Progesterone Levels: Throughout the menstrual cycle, levels of estrogen and progesterone fluctuate. If conception doesn't occur, both of these hormones decrease.
  • Uterine Lining: The fluctuation of estrogen and progesterone prepares the uterine lining for a possible pregnancy. When these hormone levels drop it signals to the uterus that a pregnancy has not occurred.
  • Prostaglandin: As you approach the end of the menstrual cycle, prostaglandin, a type of progesterone hormone, increases.
  • Uterine Contractions: The surge in prostaglandin triggers uterine contractions.
  • Shedding: These contractions cause the uterine lining to shed, resulting in menstrual bleeding – your period.

Summary of Hormonal Influence on Period Onset

Hormone Role Impact on Menstruation
Estrogen Regulates the menstrual cycle and prepares the uterine lining. Decreases before menstruation starts.
Progesterone Prepares the uterus for pregnancy. Decreases before menstruation starts; a type, prostaglandin, rises.
Prostaglandin A type of progesterone hormone that increases prior to menstruation. Triggers uterine contractions and shedding.

Example of Hormonal Impact

  • If pregnancy occurs, estrogen and progesterone levels remain high, preventing the uterine lining from shedding, and therefore, no period occurs.
  • However, if fertilization does not happen, the decrease in estrogen and progesterone allows the rise of prostaglandin which stimulates uterine contractions, leading to menstruation.

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