The bacteria that produces CAMP factor is group B streptococci (Streptococcus agalactiae).
Understanding CAMP Factor
CAMP factor is a diffusible, heat-stable protein. It plays a key role in the synergistic hemolysis observed in the CAMP test, which helps identify Streptococcus agalactiae.
- The CAMP test utilizes the synergistic interaction between Staphylococcus aureus and Streptococcus agalactiae.
- S. agalactiae produces CAMP factor.
The CAMP Test
Here’s how the CAMP test works:
- A streak of Staphylococcus aureus is made on a blood agar plate.
- The bacteria being tested (potentially Streptococcus agalactiae) is streaked perpendicular to the Staphylococcus aureus streak, without touching it.
- The plate is incubated.
- A positive CAMP test results in enhanced hemolysis (enlarged zone of clearing) at the intersection of the two streaks, due to the synergistic action of the CAMP factor from Streptococcus agalactiae and beta-lysin produced by Staphylococcus aureus.
In summary, Streptococcus agalactiae (group B streptococci) is the key bacterium known for producing the CAMP factor, making the CAMP test a crucial diagnostic tool.
