Yes, Cas9 is indeed a protein.
Cas9, short for CRISPR-associated protein 9, is a vital component in the CRISPR-Cas9 gene editing system. According to the provided reference, Cas9 (formerly called Cas5, Csn1, or Csx12) is a 160 kilodalton protein. This protein plays a crucial role in the immune defense of certain bacteria against DNA viruses and plasmids. It is also extensively used in genetic engineering applications.
Here's a breakdown of Cas9's characteristics:
- Nature: Cas9 is a protein.
- Size: It has a molecular weight of approximately 160 kDa (kilodaltons).
- Function: It acts as a molecular "scissor" to cut DNA at specific locations guided by an RNA molecule.
- Origin: It's naturally found in bacteria as part of their immune system.
- Application: It's widely used in gene editing to modify DNA sequences in various organisms.
Therefore, based on the information provided, the answer is definitively yes.