Baghdad was the great Islamic city destroyed by the Mongols.
In 1258, a significant Mongol force, commanded by Hülegü, grandson of Genghis Khan, laid siege to Baghdad. Hülegü was specifically sent from Mongolia to deal with the Abbasid Caliphate. The city fell on February 10, 1258, and the Abbasid caliph, al-Mustaʿṣim, was executed shortly after.
The destruction of Baghdad marked a significant turning point in Islamic history, demonstrating the devastating impact of the Mongol conquests on the major cultural centers of the time.