In biology, Mus refers to a genus of rodents, most notably the house mouse (Mus musculus). This species is extensively used in biological research.
Mus musculus: A Key Model Organism
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Mus musculus, the common house mouse, is frequently employed as a mammalian model in genetics and molecular biology [115].
- Genetics Research: Mice share a high degree of genetic similarity with humans, making them valuable for studying gene function and disease mechanisms.
- Molecular Biology: Their relatively short lifespan and ease of breeding allow for rapid experimentation and observation of multi-generational effects.
- Disease Modeling: Mice can be genetically modified to mimic human diseases, enabling researchers to investigate potential treatments and therapies.
Importance in Research
The widespread use of Mus musculus in research stems from several factors:
- Genetic Similarity: As noted, their genetic makeup closely resembles that of humans.
- Ease of Handling: They are relatively easy to care for and breed in laboratory settings.
- Established Resources: Extensive genetic and genomic resources are available for Mus musculus, including complete genome sequences and mutant strains.
