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What Cells Create Mucus?

Published in Mucus Production 2 mins read

Goblet cells are the primary cells responsible for creating mucus.

These specialized cells are named for their distinctive goblet, or cup-like, appearance. They originate from pluripotent stem cells and play a crucial role in maintaining the health and function of various epithelial linings in the body, such as those found in the respiratory and digestive tracts.

The main function of goblet cells is to secrete mucin, a glycoprotein that is the primary component of mucus. By secreting mucin, goblet cells form a protective mucus layer. This layer serves several vital functions, including:

  • Lubrication: Keeping surfaces moist and slippery.
  • Protection: Trapping pathogens, dust particles, and irritants, preventing them from reaching the underlying tissue.
  • Barrier: Forming a physical barrier against mechanical stress and chemical agents.

While their main role is mucus production, goblet cells are also believed to be involved in immunoregulation, contributing to the local immune response within mucosal tissues.

In summary, when asking which cells create mucus, the answer points directly to goblet cells due to their specific function of secreting mucin to form the protective mucus layer.

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