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Does PPI Affect Muscle Growth?

Published in Muscle Health 1 min read

Yes, PPI (Proton Pump Inhibitor) use has been reported to contribute to muscle function loss.

Here's a breakdown based on the reference provided:

  • PPIs and Muscle Function: The use of PPIs has been linked to a decrease in muscle function. This suggests a negative impact on muscle growth or maintenance.
  • Context Matters: The reference mentions that PPIs are often prescribed alongside NSAIDs (nonsteroidal anti-inflammatory drugs), which are anti-inflammatory. This combination, particularly in individuals with obesity, may further exacerbate muscle alterations.

In summary, while the reference doesn't directly state PPIs inhibit muscle growth, it does state they contribute to muscle function loss. This implies a negative impact on muscle health, which can indirectly affect muscle growth. Further research may be necessary to establish a definitive cause-and-effect relationship between PPI use and impaired muscle growth.

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