No, Multiple System Atrophy (MSA) is generally not considered a purely genetic disease, but genetics likely play a role in susceptibility.
While MSA is considered sporadic, meaning it typically occurs in individuals with no family history of the condition, research suggests a complex interplay of genetic, environmental, and lifestyle factors may contribute to its development. Changes in several genes are being studied as potential risk factors, but no single gene has been definitively identified as causing MSA. The precise contribution of genetics to MSA is still being investigated, and the exact cause remains unknown.
It's important to note that while specific gene mutations directly causing MSA haven't been discovered, certain genetic variations might increase an individual's susceptibility to the disease when combined with other environmental or lifestyle triggers. This means that while MSA isn't inherited in a straightforward manner like some genetic diseases, genes could still influence a person's risk of developing it.
In summary, MSA is not purely genetic, but research suggests that genetic factors may contribute to an individual's overall susceptibility to developing the condition in combination with other environmental or lifestyle influences.