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What is Akinesia?

Published in Neurology 3 mins read

Akinesia is the loss of ability to move your muscles voluntarily.

Understanding Akinesia

Akinesia, often associated with Parkinson's disease, represents a significant challenge for affected individuals. It's characterized by the difficulty or inability to initiate movement, even though the muscles themselves are not paralyzed. This is different from paralysis because the capacity for movement is still there, but the ability to start that movement is impaired.

Key Characteristics:

  • Difficulty Initiating Movement: The core issue is the struggle to begin a desired action.
  • Reduction in Spontaneous Movement: Individuals may exhibit a decrease in automatic movements like blinking, facial expressions, or swinging their arms while walking.
  • Slowness of Movement (Bradykinesia): Often co-occurs with akinesia; movements are not only hard to start but also slow to execute.
  • "Freezing" Episodes: A sudden, temporary inability to move, often occurring during walking or other activities.

Akinesia vs. Bradykinesia

While frequently linked, akinesia and bradykinesia are distinct:

Feature Akinesia Bradykinesia
Definition Difficulty or inability to initiate movement Slowness in executing movement
Primary Issue Starting movement Speed of movement
Common Manifestations Hesitation before walking, lack of facial expression Shuffling gait, difficulty with fine motor tasks

Causes and Association with Parkinson's Disease

Akinesia is most commonly seen as a symptom of Parkinson's disease (PD). In Parkinson's disease, the death of dopamine-producing cells in the brain disrupts the normal signaling pathways responsible for motor control. While Parkinson's is the most well-known link, other conditions can also cause akinesia:

  • Parkinson's Disease (PD): As mentioned, the most frequent cause.
  • Parkinsonism: A group of neurological disorders that produce similar symptoms to Parkinson's disease, such as multiple system atrophy (MSA) or progressive supranuclear palsy (PSP).
  • Other Neurological Conditions: In rare cases, it can arise from stroke, encephalitis or other brain injuries.
  • Medications: Certain medications, particularly neuroleptics (antipsychotics), can induce akinesia as a side effect. This is termed drug-induced parkinsonism.

Treatment

Treatment for akinesia is often aimed at managing the underlying condition causing it. For Parkinson's disease, treatments may include:

  • Medications: Levodopa is a common medication that helps to replenish dopamine levels in the brain.
  • Deep Brain Stimulation (DBS): A surgical procedure that involves implanting electrodes in specific areas of the brain to regulate neural activity.
  • Physical Therapy: Can help maintain mobility and improve motor skills.

It's crucial to consult with a healthcare professional for proper diagnosis and management of akinesia.

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