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What Medications Should Be Avoided in GBS?

Published in Neuromuscular Disorders 1 min read

Corticosteroids are generally avoided in the treatment of Guillain-Barré Syndrome (GBS).

While corticosteroids are highly effective for treating chronic inflammatory demyelinating polyneuropathy (CIDP), another autoimmune neuropathy, they have not shown benefit and may even be detrimental in GBS. Clinical trials have consistently failed to demonstrate any positive impact of corticosteroids on the recovery or outcome of GBS.

Here's a breakdown:

  • Corticosteroids (e.g., Prednisone, Methylprednisolone): These are the primary medications to avoid. Their use has not been shown to improve outcomes in GBS and could potentially worsen the condition or prolong recovery.

The standard treatments for GBS, such as intravenous immunoglobulin (IVIg) and plasma exchange, are the preferred methods for managing the condition. It is important to consult with a neurologist experienced in neuromuscular disorders for proper diagnosis and treatment planning.

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