Neurons are the cells with the longest lifespan in the human body. Unlike many other cells that regularly die and regenerate, many neurons persist throughout a person's entire life. Their mature form resists cell division, meaning they don't create new cells after fetal development. This longevity is crucial for maintaining long-term memory and other essential functions of the nervous system.
Understanding Neuronal Longevity
Several sources confirm the exceptional lifespan of neurons:
- National Institute of Neurological Disorders and Stroke (NINDS): States that neurons are the longest-living cells in the body. https://www.ninds.nih.gov/health-information/public-education/brain-basics/brain-basics-life-and-death-neuron
- Science Focus: While not explicitly stating neurons as the absolute longest-lived, the article highlights that some cells, implying neurons, persist for a person's entire lifetime. https://www.sciencefocus.com/the-human-body/what-cells-in-the-human-body-live-the-longest
- Quora: Reinforces that neurons, specifically citing the sciatic nerve as an example, are the longest-lived cells. https://www.quora.com/What-is-the-oldest-cell-in-the-human-body-Which-type-lives-the-longest-What-is-that-average-age-Why-do-they-live-the-longest-and-how-What-if-they-didnt
It's important to note that while other cell types, such as some stem cells, have the potential for long lifespans, neurons consistently demonstrate the greatest longevity in situ within the body.