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How do neurons move?

Published in Neuroscience 3 mins read

Neurons themselves don't "move" in the sense of locomotion like an animal. Instead, they extend and migrate during development and can shift position and change connections throughout life. The question likely refers to how neurons cause movement in the body. Here's a breakdown of how that happens:

Neurons and Muscle Movement: A Chain of Events

Movement results from a complex interplay between the nervous system (specifically, motor neurons) and the muscular system. Here's a simplified explanation:

  1. Brain's Decision: The brain decides to initiate a movement (e.g., lifting a finger).

  2. Signal Transmission: This decision is translated into electrical signals that travel down the spinal cord.

  3. Motor Neuron Activation: The signals activate motor neurons. These specialized nerve cells connect the central nervous system (brain and spinal cord) to muscles.

  4. Neurotransmitter Release: At the neuromuscular junction (the point where the motor neuron meets the muscle fiber), the motor neuron releases a chemical neurotransmitter called acetylcholine.

  5. Muscle Fiber Stimulation: Acetylcholine diffuses across the junction and binds to receptors on the muscle fiber membrane. This binding triggers a chain of events within the muscle fiber, leading to its contraction.

  6. Muscle Contraction: The muscle fiber shortens, pulling on the attached bone, resulting in movement.

  7. Signal Termination: Acetylcholine is quickly broken down, preventing continuous muscle stimulation. This allows the muscle to relax.

Neuron Migration During Development

It's important to note that during development, neurons do move. This process is crucial for proper brain formation.

  • Early Development: Newly born neurons migrate from their birthplace (often the ventricular zone) to their final destinations in the developing brain.

  • Guidance Cues: These neurons follow chemical and physical cues provided by other cells and structures in the brain.

  • Migration Mechanisms: Migration involves complex cellular mechanisms, including the extension of a leading process (like a "nose") and the translocation of the cell body.

In Summary

While mature neurons don't actively move their location, their connections are constantly changing, and they facilitate movement through the release of neurotransmitters at the neuromuscular junction, causing muscle fibers to contract. During development, however, neuronal migration is crucial for the correct formation of the nervous system.

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