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Which cells secrete CSF?

Published in Neuroscience 2 mins read

The cells that secrete cerebrospinal fluid (CSF) are specialized ependymal cells located within the choroid plexus.

The choroid plexus, found in the ventricles of the brain, is the primary site of CSF production. These ependymal cells aren't just any ependymal cells; they are highly modified to perform the crucial task of filtering blood and actively transporting substances to create CSF.

Here's a breakdown:

  • Ependymal Cells: These are glial cells that line the ventricles of the brain and the central canal of the spinal cord. In the choroid plexus, they form a single layer.
  • Choroid Plexus: This specialized structure, found within the ventricles, consists of capillaries surrounded by this layer of modified ependymal cells. It's here that the magic happens.
  • CSF Secretion Process: The ependymal cells filter blood plasma, selectively transporting ions, nutrients, and water into the ventricles. This active transport process creates the CSF, which differs significantly from blood plasma in its composition. It has lower protein levels and different ion concentrations.

In summary, the choroid plexus, specifically the modified ependymal cells within it, is responsible for the production and secretion of CSF.

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