Certain diseases can contribute to weight gain and obesity. These are often related to hormonal imbalances or medical treatments.
Hormone-Related Conditions
Several hormonal disorders can disrupt the body's metabolism and lead to weight gain:
- Underactive Thyroid: When the thyroid gland doesn't produce enough thyroid hormone (hypothyroidism), it can slow down metabolism, leading to weight gain.
- Cushing Syndrome: This condition is characterized by prolonged exposure to high levels of cortisol, a hormone produced by the adrenal glands. This can lead to weight gain, particularly in the face, neck, and abdomen.
- Polycystic Ovary Syndrome (PCOS): This hormonal disorder, common in women of reproductive age, can cause weight gain, insulin resistance, and other symptoms.
Medication-Induced Weight Gain
Some medications can also cause weight gain as a side effect:
- Corticosteroids: These drugs, often used to reduce inflammation, can increase appetite and cause weight gain.
- Antidepressants: Certain antidepressants can affect metabolism or appetite, leading to weight gain in some individuals.
- Seizure Medicines: Some anti-seizure medications are associated with weight gain as a potential side effect.
Summary Table
| Condition | Mechanism |
|---|---|
| Underactive Thyroid (Hypothyroidism) | Slows down metabolism due to low thyroid hormone levels. |
| Cushing Syndrome | Prolonged exposure to high cortisol levels, increases appetite & fat deposition. |
| Polycystic Ovary Syndrome (PCOS) | Hormonal imbalance, insulin resistance contributing to weight gain. |
| Corticosteroid Medications | Increase appetite and alter metabolism. |
| Antidepressant Medications | Affect metabolism or appetite. |
| Anti-Seizure Medications | Possible side effect of weight gain. |
It is important to note that if you are experiencing unexplained weight gain, consult a healthcare professional to rule out underlying medical conditions.
