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What is Thygeson's syndrome?

Published in Ophthalmology 2 mins read

Thygeson's superficial punctate keratitis (TSPK), also known as Thygeson's syndrome, is an uncommon eye condition characterized by recurring episodes of small, elevated, whitish-gray spots (opacities) on the cornea, the clear front surface of the eye. These opacities typically affect both eyes and are located within the surface layer (epithelium) of the cornea.

Characteristics of Thygeson's Superficial Punctate Keratitis (TSPK)

  • Chronic and Recurrent: The condition is known for its long-term nature and tendency to recur after periods of remission.
  • Corneal Opacities: Small, elevated, whitish-gray spots appear on the cornea.
  • Bilateral: Typically affects both eyes.
  • Intraepithelial: The opacities are located within the epithelium, the outermost layer of the cornea.
  • Symptoms: Common symptoms include:
    • Foreign body sensation (feeling like something is in the eye)
    • Photophobia (sensitivity to light)
    • Tearing
    • Blurred vision

Diagnosis and Treatment

Diagnosis is primarily based on clinical examination by an ophthalmologist. Treatment typically involves:

  • Lubricating eye drops: To alleviate dryness and irritation.
  • Topical corticosteroids: To reduce inflammation during flare-ups.
  • Bandage contact lenses: May be used to protect the cornea and promote healing.
  • Other Medications: In some cases, other medications like cyclosporine eye drops may be considered.

While TSPK can be bothersome, it is generally not sight-threatening and can be managed effectively with appropriate treatment.

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