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What in Saliva Kills Bacteria?

Published in Oral Microbiology 2 mins read

Saliva contains several antimicrobial agents that actively combat bacteria.

Key Antimicrobial Components in Saliva

Saliva's ability to protect us from harmful bacteria relies on a variety of compounds, with some of the most important being:

  • Hydrogen Peroxide: This is a powerful oxidizing agent that disrupts bacterial cell structures.
  • Lactoferrin: This protein binds to iron, making it unavailable for bacteria to use for growth.
  • Lysozymes: These enzymes break down bacterial cell walls, leading to cell death.

These components work together to create an environment hostile to bacterial growth, thereby safeguarding the mouth and overall health.

How These Components Work

Component Mechanism of Action
Hydrogen Peroxide Oxidizes and damages bacterial cells.
Lactoferrin Binds to iron, depriving bacteria of this essential growth nutrient.
Lysozymes Breaks down the peptidoglycan layer of bacterial cell walls, causing lysis.

These antimicrobial actions are crucial in maintaining oral hygiene and preventing infections.

Saliva's Role in Overall Health

Saliva plays a vital role in oral health, by:

  • Neutralizing acids produced by bacteria
  • Removing food debris
  • Aiding in the digestion process

The antimicrobial properties of saliva, due to the presence of hydrogen peroxide, lactoferrin, and lysozymes [3, 5], help maintain a balanced microbial environment in the mouth and prevent bacterial overgrowth.

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