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Can O+ donate liver to B+?

Published in Organ Donation Compatibility 2 mins read

Yes, someone with O+ blood type can potentially donate a liver to someone with B+ blood type, depending on other compatibility factors. People with type O blood are considered "universal donors."

Blood Type Compatibility for Liver Donation

Here's a breakdown based on the provided reference:

  • Type O donors: Can donate to any blood type (A, B, AB, and O).
  • Type B donors: Can donate to type B and AB recipients.
  • Type A donors: Can donate to type A and AB recipients.

This blood type compatibility makes O+ a suitable donor for B+. However, blood type is not the only consideration.

Additional Compatibility Factors

While O+ blood can theoretically donate to B+, liver transplantation requires careful matching beyond just ABO blood type. Other crucial factors include:

  • Tissue Typing (HLA Matching): Matching human leukocyte antigens (HLA) is vital to reduce the risk of rejection.
  • Crossmatching: This test determines if the recipient has antibodies against the donor's cells. A positive crossmatch means the recipient's body would likely reject the donor organ immediately.
  • Size Matching: The size of the donor liver must be appropriate for the recipient.
  • Overall Health of Donor and Recipient: Assessing the overall health of both the donor and recipient is critical for a successful transplant.

In conclusion, while blood type compatibility is a primary factor and O+ is generally compatible with B+, the final decision on whether a liver transplant is suitable depends on a comprehensive evaluation of all compatibility factors.

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