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Can you transplant the pancreas?

Published in Organ Transplantation 2 mins read

Yes, the pancreas can be transplanted. A pancreas transplant is a surgical procedure where a healthy pancreas from a deceased donor is implanted into a person with diabetes, typically type 1 diabetes, whose own pancreas doesn't produce enough insulin.

What Happens During a Pancreas Transplant?

During a pancreas transplant:

  • The diseased pancreas is usually not removed. It remains in your body.
  • The new, healthy pancreas is surgically placed in your abdomen.
  • The surgeon connects the donor pancreas to your blood vessels, allowing it to receive the blood supply it needs to function.
  • The donor pancreas is also connected to your digestive system, usually the small intestine, so its digestive enzymes can drain properly.

Why Get a Pancreas Transplant?

The primary goal of a pancreas transplant is to restore normal insulin production and eliminate the need for insulin injections. A successful transplant can:

  • Improve blood sugar control.
  • Reduce or eliminate complications associated with diabetes, such as kidney damage, nerve damage, and eye damage.
  • Improve quality of life by freeing you from the burden of daily insulin injections.

Who is a Candidate for a Pancreas Transplant?

Ideal candidates for a pancreas transplant are individuals with:

  • Type 1 diabetes.
  • Severe hypoglycemia (low blood sugar) unawareness.
  • Kidney damage or failure (in which case a combined kidney-pancreas transplant may be considered).
  • Significant diabetes-related complications.

What are the Risks?

As with any major surgery, pancreas transplants carry risks, including:

  • Rejection of the donor pancreas by the recipient's body.
  • Infection.
  • Bleeding.
  • Blood clots.
  • Pancreatitis.

Immunosuppressant medications are required after a transplant to prevent rejection, and these medications can have side effects.

Types of Pancreas Transplants

There are different types of pancreas transplants:

  • Pancreas Transplant Alone (PTA): This is performed on individuals with type 1 diabetes and well-functioning kidneys.
  • Simultaneous Pancreas-Kidney Transplant (SPK): This is performed on individuals with both type 1 diabetes and kidney failure.
  • Pancreas-After-Kidney Transplant (PAK): This is performed on individuals who have already received a kidney transplant but still require a pancreas transplant for diabetes management.

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