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How does iron pick up oxygen?

Published in Oxygen Transport 2 mins read

Iron, specifically within the context of hemoglobin, picks up oxygen through a direct chemical bond. Here's a detailed look at the process:

Hemoglobin and Heme

  • Hemoglobin: This is a protein found in red blood cells that's essential for carrying oxygen throughout the body. It’s composed of four subunits.
  • Heme Group: Each of hemoglobin’s four subunits contains a heme group. This heme group is the crucial element for oxygen binding. [6]

The Key Role of Iron

Within each heme group, there's a single iron atom. This iron atom is the direct binding site for oxygen. [7]

Oxygen Binding Process

  1. Direct Binding: One molecule of oxygen (O2) can bind directly to the iron atom within a heme group. [7]
  2. Four Binding Sites: Because each hemoglobin molecule has four heme groups, it can carry four oxygen molecules. [7]
  3. Transportation: Once oxygen is bound, the hemoglobin, now loaded with oxygen, transports it throughout the body to cells that need it.


Here's a table summarizing the key elements:

Element Function
Hemoglobin Protein in red blood cells, carries oxygen
Heme group Part of hemoglobin containing iron
Iron atom Directly binds to oxygen molecules
Oxygen (O2) Molecule that binds to iron for transport



In essence, iron atoms located within the heme groups of hemoglobin serve as the direct docking points for oxygen molecules, enabling them to be transported around the body.

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