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What are Pain Fibres?

Published in Pain Physiology 2 mins read

Pain fibres are nerve fibres that transmit pain signals from the body to the brain. The brain processes these signals and initiates a response to stop the painful action. There are two main types of pain fibres that are responsible for the transmission of pain:

Types of Pain Fibres

Here's a breakdown of the two major types:

Feature Myelinated A-delta Fibers Unmyelinated C Fibers
Myelination Present (Myelinated) Absent (Unmyelinated)
Speed Fast Slow
Size Larger Smaller
Pain Type Sharp, localized pain Dull, aching, diffused pain
Example Quick pain from a pinprick Lingering pain after a bruise

Understanding the Differences

  • A-delta Fibres: These fibres are myelinated, meaning they have a protective layer of myelin around them. This myelin layer acts like insulation on a wire and speeds up the transmission of nerve signals. As a result, A-delta fibres transmit pain signals quickly. This explains why you immediately feel a sharp and localized pain when you stub your toe.

  • C Fibres: In contrast, C fibres are unmyelinated, lacking the protective layer. This results in slower transmission of pain signals. C fibres are responsible for the dull, aching, or burning pain that is often associated with inflammation or ongoing discomfort.

How Pain Signals Work

  1. Stimulation: When an injury or harmful stimulus occurs, pain receptors are activated.
  2. Transmission: These activated pain receptors then send signals through either A-delta fibres (for quick, sharp pain) or C fibres (for slower, dull pain).
  3. Processing: These pain signals travel along the nerve fibres towards the spinal cord and brain.
  4. Reaction: The brain processes the incoming pain signals. Then, in response, the brain triggers motor responses to make an attempt to cease the pain-causing action.

Practical Insights

  • The differences in the speed of pain transmission explain why you may feel an immediate sharp pain, followed by a more dull, aching pain.
  • Understanding these differences can aid in pain management strategies, as different types of pain may require different approaches for relief.

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