This question is unclear and grammatically incorrect. A better phrasing might be: "Which city is Pakistan's largest?" or "Which city is considered the most important in Pakistan?". Since the original question is vague, it's impossible to provide a definitive answer. However, here's a breakdown of potential interpretations and answers:
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If the question refers to the largest city:
Karachi is the largest city in Pakistan by population.
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If the question refers to the most important city (economically/financially):
Karachi is generally considered the financial and economic hub of Pakistan, making it a major part of the country's economic activity.
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If the question refers to the capital city:
Islamabad is the capital of Pakistan. While important, it is not the only major part.
Due to the ambiguity of the original question, it's difficult to provide a single definitive answer. However, based on the reference provided, the intent seems to be asking for the largest city.
