The exocrine pancreas can regenerate spontaneously and robustly in both animals and humans.
This regeneration is significant because the exocrine pancreas, responsible for producing digestive enzymes, is composed of specialized cells that can be damaged by various factors. These cells include:
- Acinar cells: Synthesize and secrete digestive enzymes.
- Ductal cells: Funnel these enzymes into the small intestine.
- Central acinar cells: Contribute to the structure and function of the exocrine pancreas.
The ability of the exocrine pancreas to regenerate offers potential therapeutic avenues for pancreatic disorders.
