A PP cell is an alternative name for an F cell, a specific type of endocrine cell found in the pancreas.
Understanding PP Cells
PP cells, also known as F cells, are located within the islets of Langerhans in the pancreas. These specialized cells are responsible for producing and secreting a particular peptide hormone called Pancreatic Polypeptide (PP) (1).
The secretion of Pancreatic Polypeptide by PP cells typically occurs postprandially, meaning after a meal (1).
Role of Pancreatic Polypeptide Secreted by PP Cells
The Pancreatic Polypeptide (PP) released by PP cells plays a significant role in the regulation of digestion. Its primary functions involve modulating the digestive process by inhibiting certain activities (2,3).
Key roles of Pancreatic Polypeptide include:
- Inhibition of gastric emptying (2,3)
- Inhibition of biliary secretion (2,3)
By performing these functions, Pancreatic Polypeptide helps to control the rate at which food moves through the digestive system and regulates the release of bile.
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