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What is the full form of F cells?

Published in Pancreatic Cells 2 mins read

The full form of F cells is Pancreatic polypeptide cells.

F cells, also known as Pancreatic polypeptide cells (PP cells), are a specific type of cell found within the pancreatic islets (Islets of Langerhans) in the pancreas. These cells are crucial for synthesizing and regulating the release of pancreatic polypeptide (PP).

Understanding F Cells (Pancreatic Polypeptide Cells)

According to the provided reference, F cells are synonymous with Pancreatic polypeptide cells.

  • Names: F cells are primarily known as Pancreatic polypeptide cells (PP cells). Historically, they were also referred to as gamma cells (γ-cells).
  • Location: They are located in the pancreatic islets, which are clusters of endocrine cells found throughout the pancreas.
  • Function: Their main function is the production and secretion of pancreatic polypeptide (PP). This hormone plays a role in regulating pancreatic secretions and appetite.

Key Aspects of F Cells

Here’s a quick overview of F cells:

Name Location Primary Hormone Produced Former Name
F cells / PP cells Pancreatic Islets Pancreatic Polypeptide Gamma cells
  • Role of Pancreatic Polypeptide: The hormone produced by F cells, pancreatic polypeptide, is released in response to food intake. It helps regulate digestive processes, such as inhibiting pancreatic enzyme secretion and gallbladder contraction.
  • Clinical Significance: Dysregulation of PP secretion from F cells can be associated with certain conditions, although they are less commonly discussed than the hormones produced by other islet cells like insulin (from beta cells) or glucagon (from alpha cells).

Understanding the specific cell types within the pancreas, like F cells, highlights the complex endocrine function of this vital organ beyond its well-known role in glucose metabolism.

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