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Who Secretes Glucagon?

Published in Pancreatic Hormones 2 mins read

Glucagon is secreted by specific cells within the pancreas.

The Secretory Cells: Alpha Cells

The hormone glucagon is produced by alpha cells, which are located within the pancreatic islets of Langerhans. These islets are clusters of endocrine cells scattered throughout the pancreas.

  • Pancreatic Islets: These specialized areas house the endocrine cells responsible for producing hormones like insulin and glucagon.
  • Alpha Cells: Specifically, the alpha cells within these islets are tasked with synthesizing and releasing glucagon.


The reference provided states, "Glucagon is a peptide hormone secreted from the alpha cells of the pancreatic islets of Langerhans."


Function of Glucagon

Glucagon plays a crucial role in glucose homeostasis, working to increase blood sugar levels when they are too low.

  • It is released in response to low blood sugar.
  • Glucagon stimulates the liver to convert stored glycogen into glucose and releases it into the bloodstream.


Cell Type Hormone Secreted Primary Function
Alpha Cells Glucagon Increases blood glucose levels
Beta Cells Insulin Decreases blood glucose levels
Delta Cells Somatostatin Regulates insulin and glucagon secretion


In summary, alpha cells within the pancreatic islets of Langerhans are responsible for secreting glucagon.

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