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Can CBC detect filaria?

Published in Parasitology 2 mins read

A Complete Blood Count (CBC) can suggest a filarial infection, particularly when it shows eosinophilia (an elevated number of eosinophils), but it cannot definitively diagnose filaria.

Here's a breakdown:

  • What a CBC is: A CBC is a common blood test that evaluates the different types of cells in your blood, including red blood cells, white blood cells, and platelets.

  • How CBC relates to Filaria:

    • Filarial infections often trigger an immune response that includes an increase in eosinophils, a type of white blood cell involved in fighting parasites. This increase is called eosinophilia.
    • Therefore, a CBC revealing eosinophilia can be a clue that a parasitic infection like filariasis might be present.
  • Why CBC is not definitive:

    • Eosinophilia can be caused by many other conditions, such as allergies, other parasitic infections, and certain medications.
    • A CBC does not directly detect the presence of the filarial worms or microfilariae (larvae) themselves.
  • Further Testing: If a CBC suggests filariasis (due to eosinophilia), further, more specific tests are needed for diagnosis. These include:

    • Microscopic examination of blood samples: To directly identify microfilariae.
    • Antigen detection tests: To detect specific filarial antigens in the blood.
    • Antibody tests: To detect antibodies against filarial worms.

In summary: A CBC can provide an initial indication of a possible filarial infection through the observation of eosinophilia, but definitive diagnosis requires more specific testing to confirm the presence of the parasite.

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