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What are the four types of peptides?

Published in Peptide Classification 2 mins read

Based on the number of amino acids they contain, the four types of peptides are: monopeptides, dipeptides, tripeptides, and tetrapeptides.


Here is a breakdown of each peptide type:


Peptide Types Explained

Peptide Type Number of Amino Acids Description
Monopeptide One A single amino acid, not typically referred to as a peptide. The term "peptide" usually refers to two or more amino acids linked together.
Dipeptide Two Formed by two amino acids joined by a peptide bond. An example would be carnosine.
Tripeptide Three Composed of three amino acids connected by peptide bonds. An example includes glutathione.
Tetrapeptide Four Made of four amino acids linked together by peptide bonds. An example is Tuftsin, an immunostimulant.


While the reference provided clearly defines these four types of peptides, it’s also important to note that:

  • Oligopeptides: These contain a few amino acids (usually 2-20), which includes di, tri, and tetrapeptides, but also includes longer chains up to 20 amino acids.
  • Polypeptides: These are long chains of amino acids (over 20). Proteins are essentially polypeptides.


Therefore, while the question specifically asks about four types defined by the reference (monopeptide, dipeptide, tripeptide and tetrapeptide) it is worth noting the broader classification. The provided information clarifies that the four types are distinguished based purely on the number of amino acids present: one, two, three, or four respectively.

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